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Slc25a19tm1Mjl
Targeted Allele Detail
Nomenclature
Symbol: Slc25a19tm1Mjl
Name: solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19; targeted mutation 1, Marjorie J Lindhurst
MGI ID: MGI:3691853
Synonyms: Slc25a19-
Gene: Slc25a19  Location: Chr11:115614178-115628281 bp, - strand  Genetic Position: Chr11, 80.91 cM, cytoband E2
Examples of Slc25a19tm1Mjl/+ control and Slc25a19tm1Mjl/Slc25a19tm1Mjl embryos at E10.5

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:115337
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc25a19 Mutation:  23 strains or lines available
References
Original:  J:115337 Lindhurst MJ, et al., Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15927-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory