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PctpR120H
Spontaneous Allele Detail
Nomenclature
Symbol: PctpR120H
Name: phosphatidylcholine transfer protein; R120H
MGI ID: MGI:3691424
Gene: Pctp  Location: Chr11:89982665-90002894 bp, - strand  Genetic Position: Chr11, 54.7 cM
Mutation
origin
Strain of Origin:  NZO
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsA G-to-A transition in exon 4 resulted in the arginine to histidine substitution at amino acid 120 (p.R120H) in NZO, NZB/BINJ and NZW/LacJ strains. This mutation renders the protein inactive. (J:114974)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Pctp Mutation:  14 strains or lines available
References
Original:  J:114974 Pan HJ, et al., A polymorphism in New Zealand inbred mouse strains that inactivates phosphatidylcholine transfer protein. FEBS Lett. 2006 Oct 30;580(25):5953-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory