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Hspa4ltm1Imad
Targeted Allele Detail
Nomenclature
Symbol: Hspa4ltm1Imad
Name: heat shock protein 4 like; targeted mutation 1, Ibrahim M Adham
MGI ID: MGI:3690321
Synonyms: Hspa4l-
Gene: Hspa4l  Location: Chr3:40744495-40796103 bp, + strand  Genetic Position: Chr3, 19.51 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:114659
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin resistance cassette. Northern blot and RT-PCR confirmed absence of transcript in mutants. Absence of protein was confirmed by Western blot of kidney and testes. (J:114659)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hspa4l Mutation:  29 strains or lines available
References
Original:  J:114659 Held T, et al., Hspa4l-deficient mice display increased incidence of male infertility and hydronephrosis development. Mol Cell Biol. 2006 Nov;26(21):8099-108
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory