About   Help   FAQ
Lcktm1Dbs
Targeted Allele Detail
Nomenclature
Symbol: Lcktm1Dbs
Name: lymphocyte protein tyrosine kinase; targeted mutation 1, David B Straus
MGI ID: MGI:3690319
Synonyms: lckW97A
Gene: Lck  Location: Chr4:129548349-129573641 bp, - strand  Genetic Position: Chr4, 63.26 cM, cytoband distal
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:114660
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted
Mutation:    Nucleotide substitutions
    The W97A mutation was inserted into exon 3. (J:114660)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lck Mutation:  59 strains or lines available
References
Original:  J:114660 Rudd ML, et al., Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development. Mol Cell Biol. 2006 Nov;26(21):7892-900
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/26/2014
MGI 5.19
The Jackson Laboratory