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Tg(tetO-EGFR*L858R)57Hev
Transgene Detail
Nomenclature
Symbol: Tg(tetO-EGFR*L858R)57Hev
Name: transgene insertion 57, Harold E Varmus
MGI ID: MGI:3690075
Synonyms: EGFRL858R, L858R57, TetO-EGFRL858R
Transgene: Tg(tetO-EGFR*L858R)57Hev  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F2
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Line 56 was also generated.

References
Original:  J:109092 Politi K, et al., Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors. Genes Dev. 2006 Jun 1;20(11):1496-510
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory