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Grhl3tm1Bogi
Targeted Allele Detail
Nomenclature
Symbol: Grhl3tm1Bogi
Name: grainyhead like transcription factor 3; targeted mutation 1, Bogi Andersen
MGI ID: MGI:3690001
Synonyms: Get-1-
Gene: Grhl3  Location: Chr4:135541888-135573630 bp, - strand  Genetic Position: Chr4, 67.76 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:114626
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCre mediated deletion was used to remove exons 4 to 7 of the locus. These exons encode the activation domain and part of the DNA-binding domain. (J:114626)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 33 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grhl3 Mutation:  45 strains or lines available
References
Original:  J:114626 Yu Z, et al., The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 1;299(1):122-36
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory