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Tg(Myh6-PRKAG2*R302Q)#Rro
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-PRKAG2*R302Q)#Rro
Name: transgene insertion #, Robert Roberts
MGI ID: MGI:3688892
Synonyms: TGR302Q
Transgene: Tg(Myh6-PRKAG2*R302Q)#Rro  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene consists of the human PRKAG2 cDNA with a substitution of an arginine for glutamine at amino acid residue 302 under the control of the cardiac specific alpha-myosin heavy chain promoter. Expression of the transgene was confirmed by Northern analysis. Three lines were made but the reference does not distinguish between them. Data may have been pooled from more than one line. (J:108102)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:108102 Sidhu JS, et al., Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome. Circulation. 2005 Jan 4;111(1):21-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory