About   Help   FAQ
Spi1tm2.1Dgt
Targeted Allele Detail
Nomenclature
Symbol: Spi1tm2.1Dgt
Name: spleen focus forming virus (SFFV) proviral integration oncogene; targeted mutation 2.1, Daniel G Tenen
MGI ID: MGI:3688440
Synonyms: PU.1-
Gene: Spi1  Location: Chr2:91082390-91115756 bp, + strand  Genetic Position: Chr2, 50.44 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:114150
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele is a derivative of Spfi1tm2Dgt in which the sequences flanked by loxP sites in introns 3 and 5 were deleted by Cre-mediated recombination in ES cells prior to the production of chimeric mice. (J:114150)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spi1 Mutation:  14 strains or lines available
References
Original:  J:114150 Iwasaki H, et al., Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation. Blood. 2005 Sep 1;106(5):1590-600
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory