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Apctm2Rak
Targeted Allele Detail
Nomenclature
Symbol: Apctm2Rak
Name: adenomatosis polyposis coli; targeted mutation 2, Raju Kucherlapati
MGI ID: MGI:3688435
Synonyms: Apc580S, ApcCKO
Gene: Apc  Location: Chr18:34220924-34318608 bp, + strand  Genetic Position: Chr18, 18.53 cM
Stunted growth, short whiskers, sparse hair coat and abnormal tooth development in the Apctm2Rak/Apctm2Rak Tg(KRT14-cre)8Brn/0 mouse

Show the 4 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:114152
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Floxed/Frt)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apc Mutation:  49 strains or lines available
References
Original:  J:114152 Kuraguchi M, et al., Adenomatous Polyposis Coli (APC) is required for normal development of skin and thymus. PLoS Genet. 2006;2(9):e146
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory