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Epha2Gt(KST085)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: Epha2Gt(KST085)Byg
Name: Eph receptor A2; gene trap KST085, BayGenomics
MGI ID: MGI:3688255
Synonyms: Epha2-
Gene: Epha2  Location: Chr4:141301240-141329384 bp, + strand  Genetic Position: Chr4, 73.67 cM, cytoband D-E
Mutation
origin
Mutant Cell Line:  KST085 (BayGenomics)
Germline Transmission:  Earliest citation of germline transmission: J:112120
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT1TMpfs     Vector Type: secretory trap
 
Mutation details
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Epha2 Mutation:  58 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References
Original:  J:112120 Guo H, et al., Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin. Cancer Res. 2006 Jul 15;66(14):7050-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory