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Pth1rtm1Abas
Targeted Allele Detail
Nomenclature
Symbol: Pth1rtm1Abas
Name: parathyroid hormone 1 receptor; targeted mutation 1, Abdul B Abou-Samra
MGI ID: MGI:3687642
Gene: Pth1r  Location: Chr9:110722085-110747145 bp, - strand  Genetic Position: Chr9, 60.56 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113660
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Nucleotide substitutions
 
Mutation detailsA vector containing 7 serine to alanine mutations and a floxed neo-tk was inserted into the locus. The neo was subsequently removed via cre mediated recombination. (J:113660)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pth1r Mutation:  15 strains or lines available
References
Original:  J:113660 Bounoutas GS, et al., Impact of impaired receptor internalization on calcium homeostasis in knock-in mice expressing a phosphorylation-deficient parathyroid hormone (PTH)/PTH-related peptide receptor. Endocrinology. 2006 Oct;147(10):4674-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory