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Tg(TcrbBDC12-4.1)82Gse
Transgene Detail
Nomenclature
Symbol: Tg(TcrbBDC12-4.1)82Gse
Name: transgene insertion 82, George Eisenbarth
MGI ID: MGI:3687034
Synonyms: BDC12-4.1 TCR beta, beta82
Transgene: Tg(TcrbBDC12-4.1)82Gse  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
    The TCR beta (TRBV1*03/TRBJ2-7*01) chain from the BDC12-4.1 clone was subcloned into a TCR cassette. (J:111874)
Inheritance:    Dominant
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:111874 Jasinski JM, et al., Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout. Diabetes. 2006 Jul;55(7):1978-84
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory