About   Help   FAQ
Notch1tm1Pst
Targeted Allele Detail
Nomenclature
Symbol: Notch1tm1Pst
Name: notch 1; targeted mutation 1, Pamela Stanley
MGI ID: MGI:3665446
Synonyms: Notch1-
Gene: Notch1  Location: Chr2:26457903-26516663 bp, - strand  Genetic Position: Chr2, 18.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112097
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
    LoxP sites were inserted to flank exons 6-8. (J:112097)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Notch1 Mutation:  65 strains or lines available
References
Original:  J:112097 Stahl M, et al., Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1. Cancer Res. 2006 Aug 1;66(15):7562-70
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/20/2017
MGI 6.10
The Jackson Laboratory