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Igh-Jtm1Aigl
Targeted Allele Detail
Nomenclature
Symbol: Igh-Jtm1Aigl
Name: immunoglobulin heavy chain, joining region; targeted mutation 1, Antonio Iglesias
MGI ID: MGI:3665428
Synonyms: IgHMOG, Th
Gene: Igh-J  Location: unknown  Genetic Position: Chr12, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111543
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Intergenic deletion
    A rearranged VHDJH gene with a neo cassette replaced the locus replaced the DQ52/JH1-4 region. (J:111543)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igh-J Mutation:  11 strains or lines available
References
Original:  J:111543 Litzenburger T, et al., B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice. J Exp Med. 1998 Jul 6;188(1):169-80
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory