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Targeted Allele Detail
Symbol: Esr2tm1Aghe
Name: estrogen receptor 2 (beta); targeted mutation 1, A G H Ederveen
MGI ID: MGI:3665335
Synonyms: ERKObeta
Gene: Esr2  Location: Chr12:76120419-76177259 bp, - strand  Genetic Position: Chr12, 33.52 cM, cytoband D1-D3
Germline Transmission:  Earliest citation of germline transmission: J:111515
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A vector was designed to replace exon 2 and part of exon 3 with a neomycin resistance cassette. (J:111515)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esr2 Mutation:  9 strains or lines available
Original:  J:111515 Van Cromphaut SJ, et al., Intestinal calcium transporter genes are upregulated by estrogens and the reproductive cycle through vitamin D receptor-independent mechanisms. J Bone Miner Res. 2003 Oct;18(10):1725-36
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory