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Esr2tm1Aghe
Targeted Allele Detail
Nomenclature
Symbol: Esr2tm1Aghe
Name: estrogen receptor 2 (beta); targeted mutation 1, A G H Ederveen
MGI ID: MGI:3665335
Synonyms: ERKObeta
Gene: Esr2  Location: Chr12:76120419-76177259 bp, - strand  Genetic Position: Chr12, 33.52 cM, cytoband D1-D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111515
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
    A vector was designed to replace exon 2 and part of exon 3 with a neomycin resistance cassette. (J:111515)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esr2 Mutation:  8 strains or lines available
References
Original:  J:111515 Van Cromphaut SJ, et al., Intestinal calcium transporter genes are upregulated by estrogens and the reproductive cycle through vitamin D receptor-independent mechanisms. J Bone Miner Res. 2003 Oct;18(10):1725-36
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory