Cytip^tm1Wtw
Targeted Allele Detail

Summary

• Symbol: Cytip^tm1Wtw
• Name: cytohesin 1 interacting protein; targeted mutation 1, Wendy T Watford
• MGI ID: MGI:3665293
• Synonyms: Cybr^-
• Gene: Cytip Location: Chr2:58019149-58085544 bp, - strand Genetic Position: Chr2, 33.05 cM
• Alliance: Cytip^tm1Wtw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112168
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced by an EGFP with a floxed pgk neo. A stop codon was created in exon 4 by the deletion, resulting in the prevention of a transcript through alternative splicing. Mutants expressed EGFP as a fusion protein with the N-terminal part of exon 2. (J:112168)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cytip Mutation: 24 strains or lines available

References

• Original: J:112168 Watford WT, et al., Cytohesin binder and regulator (cybr) is not essential for T- and dendritic-cell activation and differentiation. Mol Cell Biol. 2006 Sep;26(17):6623-32
• All: 1 reference(s)