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Targeted Allele Detail
Symbol: Ptger4tm1.2Matb
Name: prostaglandin E receptor 4 (subtype EP4); targeted mutation 2, Matthew D Breyer
MGI ID: MGI:3665234
Synonyms: EP4del
Gene: Ptger4  Location: Chr15:5233399-5244187 bp, - strand  Genetic Position: Chr15, 1.99 cM
Germline Transmission:  Earliest citation of germline transmission: J:92301
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsDeletion of exon 2 was accomplished by taking single cell embryos carrrying an allele containing loxP sites that flank exon 2 and injecting a cre-expression plasmid. Mice were produced from the embryos that carried the deleted allele. (J:92301)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptger4 Mutation:  16 strains or lines available
Original:  J:92301 Schneider A, et al., Generation of a conditional allele of the mouse prostaglandin EP(4) receptor. Genesis. 2004 Sep;40(1):7-14
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.15
The Jackson Laboratory