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Ercc2tm3Jhjh
Targeted Allele Detail
Nomenclature
Symbol: Ercc2tm3Jhjh
Name: excision repair cross-complementing rodent repair deficiency, complementation group 2; targeted mutation 3, Jan H J Hoeijmakers
MGI ID: MGI:3664604
Synonyms: XpdG602D, XpdXPCS
Gene: Ercc2  Location: Chr7:19382010-19395694 bp, + strand  Genetic Position: Chr7, 9.62 cM
Microglia activation in the white matter in Ercc2, Ercc6, and Ercc8 mutants

Show the 1 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112689
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (knock-in)
Mutation:    Nucleotide substitutions
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ercc2 Mutation:  3 strains or lines available
References
Original:  J:112689 Andressoo JO, et al., An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria. Cancer Cell. 2006 Aug;10(2):121-32
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory