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Erap1tm1Nsha
Targeted Allele Detail
Nomenclature
Symbol: Erap1tm1Nsha
Name: endoplasmic reticulum aminopeptidase 1; targeted mutation 1, Nilabh Shastri
MGI ID: MGI:3664437
Synonyms: Arts1tm1Ucb, ERAAP-KO
Gene: Erap1  Location: Chr13:74639624-74692537 bp, + strand  Genetic Position: Chr13, 40.48 cM, cytoband C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112389
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 4-8 were replaced by a neomycin resistance gene. (J:112389)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Erap1 Mutation:  39 strains or lines available
References
Original:  J:112389 Hammer GE, et al., The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules. Nat Immunol. 2006 Jan;7(1):103-12
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory