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Pyytm1(cre)Hhzg
Targeted Allele Detail
Summary
Symbol: Pyytm1(cre)Hhzg
Name: peptide YY; targeted mutation 1, H Herzog
MGI ID: MGI:3664105
Synonyms: Pyy-
Gene: Pyy  Location: Chr11:101997502-101998658 bp, - strand  Genetic Position: Chr11, 65.48 cM
Alliance: Pyytm1(cre)Hhzg page
Greater bone mass in Pyytm1(cre)Hhzg/Pyytm1(cre)Hhzg mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111480
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Pyytm1(cre)Hhzg expression driven by 1 gene
 
Mutation detailsA vector was designed to knock out gene function but allow the endogenous promoter to drive expression of cre-recombinase by inducible tetracycline promoter regulation. (J:111480)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pyy (mouse)
Summary of all recombinase alleles driven by Pyy.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pyy Mutation:  9 strains or lines available
References
Original:  J:111480 Boey D, et al., Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity. Diabetologia. 2006 Jun;49(6):1360-1370
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory