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Elavl4tm1Okn
Targeted Allele Detail
Nomenclature
Symbol: Elavl4tm1Okn
Name: ELAV like RNA binding protein 4; targeted mutation 1, Hideyuki Okano
MGI ID: MGI:3664094
Synonyms: HuD-
Gene: Elavl4  Location: Chr4:110203722-110351909 bp, - strand  Genetic Position: Chr4, 51.42 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97282
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1 kb fragment including the exon containing the initiation site was replaced with a PGK-neo cassette via homologous recombination. RT-PCR analysis of adult brain and immunoblot analysis of adult brain and liver confirmed the absence of message and protein in homozygotes. (J:97282)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Elavl4 Mutation:  24 strains or lines available
References
Original:  J:97282 Akamatsu W, et al., The RNA-binding protein HuD regulates neuronal cell identity and maturation. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4625-30
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory