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Gpr12tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Gpr12tm1Dgen
Name: G-protein coupled receptor 12; targeted mutation 1, Deltagen
MGI ID: MGI:3663376
Synonyms: Gpr12-
Gene: Gpr12  Location: Chr5:146582398-146585239 bp, - strand  Genetic Position: Chr5, 85.23 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111942
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn IRES-lacZ-pA-PGK-neo-pA cassette replaced a sequence of exon 2 corresponding to nucleotides 155-507. LacZ expression was visualized in mutant brain sections. (J:111942)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpr12 Mutation:  8 strains or lines available
References
Original:  J:111942 Bjursell M, et al., G protein-coupled receptor 12 deficiency results in dyslipidemia and obesity in mice. Biochem Biophys Res Commun. 2006 Sep 22;348(2):359-66
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory