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Atp8a1tm1Dgen
Targeted Allele Detail
Summary
Symbol: Atp8a1tm1Dgen
Name: ATPase phospholipid transporting 8A1; targeted mutation 1, Deltagen
MGI ID: MGI:3663343
Gene: Atp8a1  Location: Chr5:67775483-68004777 bp, - strand  Genetic Position: Chr5, 36.15 cM
Alliance: Atp8a1tm1Dgen page
Mutation
origin
Mutant Cell Line:  5014
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA LacZ-neomycin cassette was inserted into the gene so that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts were detected in all tissues analysed. LacZ expression was detected in most tissues examined, particularly nervous system and lungs. No LacZ expression was detected in lymph nodes, aorta, liver, or pancreas. (J:101679)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 78 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atp8a1 Mutation:  72 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory