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Slc40a1ffe
Chemically induced Allele Detail
Nomenclature
Symbol: Slc40a1ffe
Name: solute carrier family 40 (iron-regulated transporter), member 1; flatiron
MGI ID: MGI:3662903
Synonyms: ffeH32R, Fpnffe
Gene: Slc40a1  Location: Chr1:45908068-45926523 bp, - strand  Genetic Position: Chr1, 23.96 cM, cytoband B
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis allele contains an A to G transition at position 95 in the coding sequence, resulting in an H32R substitution in the signal sequence. (J:118592)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc40a1 Mutation:  27 strains or lines available
References
Original:  J:118592 Zohn IE, et al., The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease. Blood. 2007 May 15;109(10):4171-80
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory