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Tg(H2-K-Cd86)7All
Transgene Detail
Nomenclature
Symbol: Tg(H2-K-Cd86)7All
Name: transgene insertion 7, James P Allison
MGI ID: MGI:3656399
Synonyms: B7.2hi
Transgene: Tg(H2-K-Cd86)7All  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(H2-K-Cd86)7All expresses 1 gene
 
Mutation detailsA construct in which Cd86 cDNA containing the coding region was placed under control of the H2-Kb promoter and immunoglobulin heavy chain enhancer was used to create the transgene. Line 7 showed high levels of Cd86 expression on B lymphocytes. (J:112475)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:112475 Fournier S, et al., T cell-mediated elimination of B7.2 transgenic B cells. Immunity. 1997 Mar;6(3):327-39
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/10/2019
MGI 6.14
The Jackson Laboratory