Slc45a2^uw-5J
Spontaneous Allele Detail

Summary

• Symbol: Slc45a2^uw-5J
• Name: solute carrier family 45, member 2; underwhite 5 Jackson
• MGI ID: MGI:3656018
• Gene: Slc45a2 Location: Chr15:11000807-11029319 bp, + strand Genetic Position: Chr15, 5.4 cM
• Alliance: Slc45a2^uw-5J page

Mutation origin

• Strain of Origin: B6.Cg-H2^g7 Tg(Ins2-CD80)3B7Flv/LwnJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Sequencing of all exons of the gene identified a G-to-A transition in exon 6 that replaces glycine (GGA) with arginine (AGA) in the very highly evolutionarily conserved protein. Failure to complement another mutation at this locus, underwhite 4 Jackson, suggests that these mutations are responsible for the phenotype. (J:112288)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc45a2 Mutation: 55 strains or lines available

References

• Original: J:112288 Gwynn B, et al., A spontaneous mutation in Slc45a2 (underwhite) reduces coat color pigmentation. MGI Direct Data Submission. 2006
• All: 1 reference(s)