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Rab3gap1tm1Tkss
Targeted Allele Detail
Nomenclature
Symbol: Rab3gap1tm1Tkss
Name: RAB3 GTPase activating protein subunit 1; targeted mutation 1, Takuya Sasaki
MGI ID: MGI:3654149
Gene: Rab3gap1  Location: Chr1:127868773-127943868 bp, + strand  Genetic Position: Chr1, 55.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111069
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA targeting vector was designed to replace most of exon 1 and all of exon 2 with a neomycin resistance gene. (J:111069)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rab3gap1 Mutation:  24 strains or lines available
References
Original:  J:111069 Sakane A, et al., Rab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab3. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10029-34
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory