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Ptentm2Hwu
Targeted Allele Detail
Nomenclature
Symbol: Ptentm2Hwu
Name: phosphatase and tensin homolog; targeted mutation 2, Hong Wu
MGI ID: MGI:3653409
Synonyms: Pten-
Gene: Pten  Location: Chr19:32757497-32826160 bp, + strand  Genetic Position: Chr19, 28.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110567
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsDeletion of exons 1-3 including both transcription and translation initiation sites was induced by homologous recombination. (J:71874)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pten Mutation:  35 strains or lines available
References
Original:  J:110567 Freeman D, et al., Genetic background controls tumor development in PTEN-deficient mice. Cancer Res. 2006 Jul 1;66(13):6492-6
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory