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Fgf23tm1Sliu
Targeted Allele Detail
Nomenclature
Symbol: Fgf23tm1Sliu
Name: fibroblast growth factor 23; targeted mutation 1, Shiguang Liu
MGI ID: MGI:3652903
Synonyms: Fgf23-, FGF23-eGFP+
Gene: Fgf23  Location: Chr6:127072902-127081408 bp, + strand  Genetic Position: Chr6, 61.92 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110579
Parent Cell Line:  EF1 (ES Cell)
Strain of Origin:  129S/SvEv x C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert an eGFP-neo cassette to replace immediately after the ATG in exon 1. (J:110579)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgf23 Mutation:  8 strains or lines available
References
Original:  J:110579 Liu S, et al., Pathogenic role of Fgf23 in Hyp mice. Am J Physiol Endocrinol Metab. 2006 Jul;291(1):E38-49
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory