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Rcan2tm1Jmol
Targeted Allele Detail
Nomenclature
Symbol: Rcan2tm1Jmol
Name: regulator of calcineurin 2; targeted mutation 1, Jeffery D Molkentin
MGI ID: MGI:3641543
Synonyms: mcip2-
Gene: Rcan2  Location: Chr17:43801851-44039516 bp, + strand  Genetic Position: Chr17, 19.77 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109586
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a neomycin resistance gene via homologous recombination. Wesetern blot confirmed absence of protein in mutant heart, skeletal muscle and brain. (J:109586)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rcan2 Mutation:  11 strains or lines available
References
Original:  J:109586 Sanna B, et al., Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7327-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory