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Bmp2tm1Vrs
Targeted Allele Detail
Nomenclature
Symbol: Bmp2tm1Vrs
Name: bone morphogenetic protein 2; targeted mutation 1, Vicki Rosen
MGI ID: MGI:3641368
Synonyms: Bmp2c, Bmp2clc, Bmp2flox
Gene: Bmp2  Location: Chr2:133552159-133562885 bp, + strand  Genetic Position: Chr2, 65.21 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110615
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe third exon and part of the 3' UTR were flanked by loxP sites. Excision of the floxed segment is predicted to create a non-functional protein. (J:110615)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmp2 Mutation:  5 strains or lines available
References
Original:  J:110615 Rivera-Feliciano J, et al., Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field. Dev Biol. 2006 Jul 15;295(2):580-8
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory