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Targeted Allele Detail
Symbol: Igh-Jtm1Khyk
Name: immunoglobulin heavy chain, joining region; targeted mutation 1, Kyoko Hayakawa
MGI ID: MGI:3641272
Synonyms: Vh11+ NeoR-
Gene: Igh-J  Location: unknown  Genetic Position: Chr12, Syntenic
Germline Transmission:  Earliest citation of germline transmission: J:109979
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
Mutation detailsA targeting vector was designed to insert a VH11DHJH1 gene segment into the locus, with a floxed neo. The neo was subsequently removed via cre-mediated recombination. (J:109979)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Igh-J Mutation:  14 strains or lines available
Original:  J:109979 Wen L, et al., Association of B-1 B cells with follicular dendritic cells in spleen. J Immunol. 2005 Jun 1;174(11):6918-26
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
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