Tg(Amy2-cre)1Herr
Transgene Detail

Summary

• Symbol: Tg(Amy2-cre)1Herr
• Name: transgene insertion 1, Pedro L Herrera
• MGI ID: MGI:3641201
• Synonyms: sv40/amylase-Cre
• Transgene: Tg(Amy2-cre)1Herr Location: unknown Genetic Position: Chr15, Syntenic
• Alliance: Tg(Amy2-cre)1Herr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Amy2-cre)1Herr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Amy (MGI:88018)

• Mutation details: This transgene consists of SV40 small T antigen in a reverse orientation, a 900 bp fragment of the Amy2 promoter region, cre recombinase, and a human growth hormone mini gene. Cre expression is seen in the definitive endoderm starting at E9.0 but is not seen in the liver or ventral pancreas before E12.5. The integration site was mapped to chromosome 15 in the promoter region of Zhx1. (J:110139)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Amy (mouse) Summary of all recombinase alleles driven by Amy. Comparative matrix view of recombinase activities Alliance mouse Amy gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:110139 Kockel L, et al., An amylase/cre transgene marks the whole endoderm but the primordia of liver and ventral pancreas. Genesis. 2006 Jun;44(6):287-96
• All: 2 reference(s)