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Targeted Allele Detail
Symbol: Asah2tm1Rlp
Name: N-acylsphingosine amidohydrolase 2; targeted mutation 1, Richard L Proia
MGI ID: MGI:3641171
Synonyms: NcDase-
Gene: Asah2  Location: Chr19:31962046-32080540 bp, - strand  Genetic Position: Chr19, 26.58 cM, cytoband C3
Germline Transmission:  Earliest citation of germline transmission: J:110485
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    A targeting vector was designed to produce a deletion of part of exon 17 and the entire exon 18. (J:110585)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Asah2 Mutation:  29 strains or lines available
Original:  J:110485 Kono M, et al., Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids. J Biol Chem. 2006 Mar 17;281(11):7324-31
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.20
The Jackson Laboratory