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Ryr2tm1.1Hta
Targeted Allele Detail
Nomenclature
Symbol: Ryr2tm1.1Hta
Name: ryanodine receptor 2, cardiac; targeted mutation 1.1, Hiroshi Takeshima
MGI ID: MGI:3640298
Synonyms: Crrm2
Gene: Ryr2  Location: Chr13:11553103-12106945 bp, - strand  Genetic Position: Chr13, 4.38 cM, cytoband A1-A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48277
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsTransient expression of cre recombinase in ES cells removed the first protein coding sequence of 48 base pairs and part of the first intron. (J:48277)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ryr2 Mutation:  38 strains or lines available
References
Original:  J:48277 Takeshima H, et al., Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2. EMBO J. 1998 Jun 15;17(12):3309-16
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory