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Itgb1tm1.1Efu
Targeted Allele Detail
Nomenclature
Symbol: Itgb1tm1.1Efu
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 1.1, Elaine Fuchs
MGI ID: MGI:3639561
Synonyms: Itgb1-
Gene: Itgb1  Location: Chr8:128685654-128733200 bp, + strand  Genetic Position: Chr8, 76.09 cM, cytoband E2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108331
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsInsertion of loxP sites flanking the third exon of the Itgb1 gene. Crossing heterozygous mice with CMV-cre deleter mice to excise the floxed exon produced an Itgb1-deficient allele. (J:65039)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itgb1 Mutation:  31 strains or lines available
References
Original:  J:108331 Chen H, et al., In vivo beta1 integrin function requires phosphorylation-independent regulation by cytoplasmic tyrosines. Genes Dev. 2006 Apr 15;20(8):927-32
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/13/2017
MGI 6.10
The Jackson Laboratory