Tg(Myh6-Acsl1)M13Jesc
Transgene Detail
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Symbol: |
Tg(Myh6-Acsl1)M13Jesc |
Name: |
transgene insertion M13, Jean E Schaffer |
MGI ID: |
MGI:3639516 |
Synonyms: |
MHC-ACS M13 |
Transgene: |
Tg(Myh6-Acsl1)M13Jesc Location: unknown
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Alliance: |
Tg(Myh6-Acsl1)M13Jesc page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Myh6-Acsl1)M13Jesc expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Acsl1 (MGI:102797) |
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Tg(Myh6-Acsl1)M13Jesc expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Myh6 (MGI:97255) |
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Mutation details: The murine adipocyte Acsl1 cDNA containing a Myc tag is under the control of an alpha-mysoin heavy chain promoter construct that contains the last exon of the beta-myosin heavy chain gene, the alpha-myosin heavy chain promoter, and the first three untranslated exons of the alpha-myosin heavy chain gene. See a 9-fold increase in Acsl1 protein specifically in the heart.
(J:68639)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:68639 Chiu HC, et al., A novel mouse model of lipotoxic cardiomyopathy. J Clin Invest. 2001 Apr;107(7):813-22 |
All: |
1 reference(s) |
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