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Fgf8tm2Moon
Targeted Allele Detail
Nomenclature
Symbol: Fgf8tm2Moon
Name: fibroblast growth factor 8; targeted mutation 2, Anne M Moon
MGI ID: MGI:3639320
Synonyms: Fgf8c
Gene: Fgf8  Location: Chr19:45736798-45742915 bp, - strand  Genetic Position: Chr19, 38.75 cM, cytoband C3-D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109475
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 4, an frt-flanked neo and a second loxP site was inserted into the 3' UTR. (J:109475)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 11 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf8 Mutation:  11 strains or lines available
References
Original:  J:109475 Park EJ, et al., Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling. Development. 2006 Jun;133(12):2419-33
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory