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Dkk2tm1Lmgd
Targeted Allele Detail
Summary
Symbol: Dkk2tm1Lmgd
Name: dickkopf WNT signaling pathway inhibitor 2; targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
MGI ID: MGI:3639316
Synonyms: Dkk2-
Gene: Dkk2  Location: Chr3:131791053-131886065 bp, + strand  Genetic Position: Chr3, 61.32 cM, cytoband H2
Alliance: Dkk2tm1Lmgd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109481
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The entire first exon was replaced with a PGK-neo cassette. (J:109481)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dkk2 Mutation:  22 strains or lines available
References
Original:  J:109481 Mukhopadhyay M, et al., Dkk2 plays an essential role in the corneal fate of the ocular surface epithelium. Development. 2006 Jun;133(11):2149-54
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory