Hr^rh-Chr
Spontaneous Allele Detail

Summary

• Symbol: Hr^rh-Chr
• Name: lysine demethylase and nuclear receptor corepressor; rhino Christiano
• MGI ID: MGI:3630275
• Gene: Hr Location: Chr14:70789652-70810988 bp, + strand Genetic Position: Chr14, 36.32 cM
• Alliance: Hr^rh-Chr page

Mutation origin

• Strain of Origin: wild

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A C-to-T transition mutation at codon 467 results in an arginine to stop codon alteration (p.R467*) in the encoded protein. (J:53633)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hr Mutation: 84 strains or lines available

References

• Original: J:53633 Ahmad W, et al., Molecular basis of a novel rhino (hr(rhChr)) phenotype: a nonsense mutation in the mouse hairless gene. Exp Dermatol. 1998 Oct;7(5):298-301
• All: 1 reference(s)