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Cst10tm1Hkaw
Targeted Allele Detail
Nomenclature
Symbol: Cst10tm1Hkaw
Name: cystatin 10 (chondrocytes); targeted mutation 1, Hiroshi Kawaguchi
MGI ID: MGI:3629665
Synonyms: Cst10-
Gene: Cst10  Location: Chr2:149405057-149410293 bp, + strand  Genetic Position: Chr2, 73.8 cM, cytoband G
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109550
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exon 1 with a pgk-neo cassette. Neither transcripts nor protein was detected in mutant rib cartilage. (J:109550)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cst10 Mutation:  6 strains or lines available
References
Original:  J:109550 Yamada T, et al., Carminerin contributes to chondrocyte calcification during endochondral ossification. Nat Med. 2006 Jun;12(6):665-70
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/13/2017
MGI 6.10
The Jackson Laboratory