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Cxcl1tm1Wabo
Targeted Allele Detail
Nomenclature
Symbol: Cxcl1tm1Wabo
Name: chemokine (C-X-C motif) ligand 1; targeted mutation 1, William A Boisvert
MGI ID: MGI:3629087
Synonyms: KC-, KC/GRO-alpha-
Gene: Cxcl1  Location: Chr5:90891241-90893115 bp, + strand  Genetic Position: Chr5, 44.78 cM, cytoband E-F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107325
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance cassette was inserted into the locus. (J:107325)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cxcl1 Mutation:  6 strains or lines available
References
Original:  J:107325 Boisvert WA, et al., Up-regulated expression of the CXCR2 Ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression. Am J Pathol. 2006 Apr;168(4):1385-95
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory