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Kdrtm1.1Jrt
Targeted Allele Detail
Nomenclature
Symbol: Kdrtm1.1Jrt
Name: kinase insert domain protein receptor; targeted mutation 1.1, Janet Rossant
MGI ID: MGI:3629038
Synonyms: Flk1-lacZ neo-out
Gene: Kdr  Location: Chr5:75932827-75978458 bp, - strand  Genetic Position: Chr5, 40.23 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109435
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis allele was derived from Kdrtm1Jrt by crossing these mice to transgenic mice that ubiquitously express cre. As a result the floxed PGK-neomycin cassette was excised. (J:109435)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kdr Mutation:  10 strains or lines available
References
Original:  J:109435 Ema M, et al., Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors. Blood. 2006 Jan 1;107(1):111-7
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory