Kdr^tm1.1Jrt
Targeted Allele Detail

Summary

• Symbol: Kdr^tm1.1Jrt
• Name: kinase insert domain protein receptor; targeted mutation 1.1, Janet Rossant
• MGI ID: MGI:3629038
• Synonyms: Flk1-lacZ neo-out
• Gene: Kdr Location: Chr5:76093487-76139118 bp, - strand Genetic Position: Chr5, 40.23 cM
• Alliance: Kdr^tm1.1Jrt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109435
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was derived from Kdr^tm1Jrt by crossing these mice to transgenic mice that ubiquitously express cre. As a result the loxP site flanked neomycin resistance gene cassette was excised. (J:109435)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdr Mutation: 71 strains or lines available

References

• Original: J:109435 Ema M, et al., Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors. Blood. 2006 Jan 1;107(1):111-7
• All: 11 reference(s)