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Pdpk1tm1Maka
Targeted Allele Detail
Nomenclature
Symbol: Pdpk1tm1Maka
Name: 3-phosphoinositide dependent protein kinase 1; targeted mutation 1, Masato Kasuga
MGI ID: MGI:3628819
Synonyms: betaPdk1-, Pdk1flox, Pdk1tm1Maka
Gene: Pdpk1  Location: Chr17:24073680-24150924 bp, - strand  Genetic Position: Chr17, 12.23 cM, cytoband A3.3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109359
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted to flank exons 3 and 4. Transient cre expression removed a floxed neo that was inserted into the locus. (J:109359)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdpk1 Mutation:  119 strains or lines available
References
Original:  J:109359 Inoue H, et al., Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. Cell Metab. 2006 Apr;3(4):267-75
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory