About   Help   FAQ
Nme1tm1Jyd
Targeted Allele Detail
Summary
Symbol: Nme1tm1Jyd
Name: NME/NM23 nucleoside diphosphate kinase 1; targeted mutation 1, Jean-Yves Daniel
MGI ID: MGI:3628812
Synonyms: m1-, Nm23-M1-
Gene: Nme1  Location: Chr11:93849751-93859341 bp, - strand  Genetic Position: Chr11, 58.89 cM
Alliance: Nme1tm1Jyd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109190
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA promoterless betagal was inserted into the locus such that the ATG in exon 2 was replaced. Northern blot failed to detect transcript in mutant liver extracts. Reporter expression was detected in embryos in the epithelial layer. (J:109190)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 32 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nme1 Mutation:  25 strains or lines available
References
Original:  J:109190 Arnaud-Dabernat S, et al., Knockout mice as model systems for studying nm23/NDP kinase gene functions. Application to the nm23-M1 gene. J Bioenerg Biomembr. 2003 Feb;35(1):19-30
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory