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Shox2tm1.1Ddu
Targeted Allele Detail
Nomenclature
Symbol: Shox2tm1.1Ddu
Name: short stature homeobox 2; targeted mutation 1.1, Denis Duboule
MGI ID: MGI:3628798
Synonyms: Shox2-
Gene: Shox2  Location: Chr3:66971727-66981771 bp, - strand  Genetic Position: Chr3, 30.76 cM, cytoband E3-F1
Limb phenotype of Shox2tm1Ddu/Shox2tm1.1Ddu Tg(Prrx1-cre)1Cjt mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107668
Parent Cell Line:  P1 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Cre mediated recombination resulted in deletion of the entire coding region. (J:107668)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Shox2 Mutation:  2 strains or lines available
References
Original:  J:107668 Cobb J, et al., A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4511-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory