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Gata2tm1.1Sac
Targeted Allele Detail
Nomenclature
Symbol: Gata2tm1.1Sac
Name: GATA binding protein 2; targeted mutation 1.1, Sally A Camper
MGI ID: MGI:3628640
Synonyms: Gata2-
Gene: Gata2  Location: Chr6:88193891-88207032 bp, + strand  Genetic Position: Chr6, 39.2 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108963
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCre recombinase expression resulted in the removal of exon 5, which encodes the C-terminal zinc finger domain. Western blot did not detect a stable protein of expected size from mutants. (J:108963)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gata2 Mutation:  17 strains or lines available
References
Original:  J:108963 Charles MA, et al., Pituitary-specific gata2 knockout: effects on gonadotrope and thyrotrope function. Mol Endocrinol. 2006 Jun;20(6):1366-77
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory