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Targeted Allele Detail
Symbol: Dnmt3btm7Enl
Name: DNA methyltransferase 3B; targeted mutation 7, En Li
MGI ID: MGI:3628447
Synonyms: Dnmt3bG
Gene: Dnmt3b  Location: Chr2:153649450-153687730 bp, + strand  Genetic Position: Chr2, 75.79 cM, cytoband A2-A3
Germline Transmission:  Earliest citation of germline transmission: J:106540
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Not Specified)
Mutation:    Nucleotide substitutions
Mutation detailsA targeting vector was designed to insert a D823G substitution. Cre mediated recombination removed a floxed IRES-betageo from the locus. This allele produced protein at levels similar to those of wild-type mice. (J:106540)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dnmt3b Mutation:  30 strains or lines available
Original:  J:106540 Ueda Y, et al., Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome. Development. 2006 Mar;133(6):1183-92
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.10
The Jackson Laboratory