About   Help   FAQ
Adora2atm1.1Dyj
Targeted Allele Detail
Nomenclature
Symbol: Adora2atm1.1Dyj
Name: adenosine A2a receptor; targeted mutation 1.1, Yuan-Ji Day
MGI ID: MGI:3625456
Synonyms: A2A-, Adora2atm1.1Masc
Gene: Adora2a  Location: Chr10:75316877-75334784 bp, + strand  Genetic Position: Chr10, 38.52 cM, cytoband B5.3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:104338
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsVariable germline expression of cre disrupted the targeted allele carrying floxed exon 2 resulting in removal of exon 2 in some gonadal cells, instead of the expected tissue-specific disruption of the floxed allele by the Camk2a-cre transgene. (J:104338)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adora2a Mutation:  20 strains or lines available
References
Original:  J:104338 Bastia E, et al., A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization. Neuropsychopharmacology. 2005 May;30(5):891-900
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/10/2017
MGI 6.10
The Jackson Laboratory