About   Help   FAQ
Trat1tm1Lsmn
Targeted Allele Detail
Nomenclature
Symbol: Trat1tm1Lsmn
Name: T cell receptor associated transmembrane adaptor 1; targeted mutation 1, Luca Simeoni
MGI ID: MGI:3625134
Synonyms: TRIM-
Gene: Trat1  Location: Chr16:48734690-48771956 bp, - strand  Genetic Position: Chr16, 30.75 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108406
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 1 and exon 2, sequence encompassing the ATG and the entire transmembrane region, were replaced with a neomycin cassette. Western blot failed to detect protein in mutant thymocytes. (J:108406)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trat1 Mutation:  5 strains or lines available
References
Original:  J:108406 Kolsch U, et al., Normal T-cell development and immune functions in TRIM-deficient mice. Mol Cell Biol. 2006 May;26(9):3639-48
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/11/2017
MGI 6.08
The Jackson Laboratory