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Trat1tm1Lsmn
Targeted Allele Detail
Nomenclature
Symbol: Trat1tm1Lsmn
Name: T cell receptor associated transmembrane adaptor 1; targeted mutation 1, Luca Simeoni
MGI ID: MGI:3625134
Synonyms: TRIM-
Gene: Trat1  Location: Chr16:48734690-48771956 bp, - strand  Genetic Position: Chr16, 30.75 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108406
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 1 and exon 2, sequence encompassing the ATG and the entire transmembrane region, were replaced with a neomycin cassette. Western blot failed to detect protein in mutant thymocytes. (J:108406)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trat1 Mutation:  5 strains or lines available
References
Original:  J:108406 Kolsch U, et al., Normal T-cell development and immune functions in TRIM-deficient mice. Mol Cell Biol. 2006 May;26(9):3639-48
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory